April 11th 2023

By Ailsa Colquhoun

Tier 2 and 3 medicine supply notifications

Estradiol, Estriol, Oral Oxycodone, Clarithromycin, Alfuzosin 10mg modified release tablets

Four Tier 2 and one tier 3 medicine supply notifications have been issued for the following items:

Tier 2

  • Estradiol (Estradot) 75micrograms/24hours transdermal patches
  • Estriol (Imvaggis) 0.03mg pessary
  • Clarithromycin 125mg/5ml and 250mg/5ml oral suspensions
  • Alfuzosin 10mg modified release tablets

Tier 3

  • Oxycodone Hydrochloride 5mg/5ml Oral Solution
Medicine Out of stock Alternatives
Estradiol (Estradot) 75micrograms/24hours transdermal patches Until early May 2023   Evorel 75micrograms/24hours transdermal patches See MSN for details.  
Estriol (Imvaggis) 0.03mg pessary Until mid-late May 2023 Alternative estriol vaginal products Estradiol 10mcg vaginal tablets
Alfuzosin 10mg modified release tablets Until w/c 15 May 2023   Alternative alpha-adrenoceptor blockers are available See MSN for details  
Oxycodone Hydrochloride 5mg/5ml Oral Solution Until end of June 2023 Oxycodone 5mg and 10mg immediate release capsules Alternative liquid opioid formulations Specials oxycodone 5mg/5ml oral suspension have been sourced. See MSN for details
Clarithromycin 125mg/5ml oral suspension Clarithromycin 250mg/5ml oral suspension 125mg/5ml oral suspension – until w/c 10 April 2023 250mg/5ml oral suspension – limited supply until w/c 10 April 2023 Alternative clarithromycin preparations Serious Shortage Protocol’s (SSP) were issued on 06/04/2023 See MSN

Up-to-date information about medicine supply issues is available via the online Medicines Supply Tool (SPS registration required)    


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